Tetrahedron letters

Microwave-assisted simple, one-pot, four-component synthesis of 2, 4, 6-triarylpyrimidines under solvent-free conditions

M Adib, N Mahmoodi, M Mahdavi, HR Bijanzadeh

Index: Adib, Mehdi; Mahmoodi, Niusha; Mahdavi, Mohammad; Bijanzadeh, Hamid Reza Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9365 - 9368

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Citation Number: 17

Abstract

2,4,6-Trisubstituted pyrimidines have been synthesized using various methods and procedures including the reaction of amidines with α,β-unsaturated ketones, 11 dimerization–oxidative fragmentation of aryl-β-arylvinylimines, 12 one-pot condensation of β-dicarbonyl compounds, NH 4 OAc and aldehydes, 13 condensation of phenacyldimethylsulfonium salts, aldehydes, and ammonia, 14 reaction of alkynes and nitriles in the presence of TfOH, 15 rearrangement of 2,4,5- ...