Abstract The catalytic application of a novel palladium-containing periodic mesoporous organosilica with ionic liquid framework (Pd@ PMO-IL-I) in the Heck cross-coupling reaction was described. This nanocatalyst was first synthesised and characterised by using diffuse reflectance infrared Fourier transform spectroscopy, thermogravimetric analysis, transmission electron microscopy and nitrogen sorption analysis. The efficiency of the Pd ...