The Journal of Organic Chemistry

The reaction of various methoxy-substituted haloarenes with amines and nitriles under aryne-forming conditions

A Razzuk, ER Biehl

Index: Razzuk, Aziz; Biehl, Edward R. Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2619 - 2622

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Citation Number: 34

Abstract

Perusing the data listed in Table I reveals that those reactions in which modest size amines were used produced the corresponding anilines in good yields; whereas the yields of those reactions which employed bulky amines were generally lower in comparison to the former amines. For example, the reaction of 2 with isobutylamine and diisobutylamine gave N- isobutyl-3, 4, 5-trimethoxyaniline and N, N-diisobutyl-3, 4, 5-trimethoxyaniline in yields of ...