Life sciences

Photodegradation products of propranolol: The structures and pharmacological studies

K Uwai, M Tani, Y Ohtake, S Abe, A Maruko, T Chiba…

Index: Uwai, Koji; Tani, Marie; Ohtake, Yosuke; Abe, Shinya; Maruko, Akiko; Chiba, Takashi; Hamaya, Yoshiro; Ohkubo, Yasuhito; Takeshita, Mitsuhiro Life Sciences, 2005 , vol. 78, # 4 p. 357 - 365

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Citation Number: 21

Abstract

Recently, single-dose drug packaging systems, allowing the administration of multiple drugs in a single pill, have become popular for the convenience of the patient. The quality of drugs and an accurate measurement of their photostabilities within this system, however, have not been carefully addressed. Drugs that are unstable in light should be carefully handled to protect their potency and ensure their safety. Propranolol (1), a β-adrenergic receptor ...