The Journal of organic chemistry

Regio-and stereoselective dimerization of terminal alkynes to enynes catalyzed by a palladium/imidazolium system

C Yang, SP Nolan

Index: Yang, Chuluo; Nolan, Steven P. Journal of Organic Chemistry, 2002 , vol. 67, # 2 p. 591 - 593

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Citation Number: 89

Abstract

A Palladium/imidazolium chloride system has been used to mediate the dimerization of terminal alkynes to enynes. The combination of 1 mol% Pd (OAc) 2 and 2 mol% IMes⊙ HCl in the presence of Cs2CO3 as base shows high activity and high regio-and steroselectivity for the dimerization of aryl and aliphatic terminal alkynes to enynes.