Synlett

Microwave-Assisted One-Pot Synthesis of α-Fluoro-α, β-Unsaturated Esters under Solvent-Free Conditions

A Ren, X Yang, J Hong, X Yu

Index: Ren, Aishan; Yang, Xiongjun; Hong, Jing; Yu, Xiaochun Synlett, 2008 , # 15 p. 2376 - 2378

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Citation Number: 7

Abstract

Abstract A microwave-assisted approach for the synthesis of α-fluoro-α, β-unsaturated esters from ethyl bromofluoroacetate, aldehydes, and triphenylphosphine in the presence of Zn-Cu under solvent-free conditions was achieved. The reaction was accomplished within five minutes with good product yields.