Abstract Long-chain fatty acid esters of 7-(3, 4-dihydroxybutyloxy)-2H-1-benzopyran-2-one (6) such as octanoate 2a are shown to be exceptionally sensitive and selective fluorogenic substrates for lipases and esterases. Umbelliferone (8) is released upon hydrolysis of the ester function in 2a in the presence of bovine serum albumin and sodium periodate. These substrates are at least by one order of magnitude more sensitive to lipases than the ...
![7-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy]chromen-2-one Structure](https://image.chemsrc.com/caspic/198/646065-67-0.png)