The intramolecular silyl-modified Sakurai (ISMS) reaction. A simple and versatile synthesis of tetrahydropyrans, spiro ethers, and spiro ketals

…, A Mekhalfia, DJ Bayston, H Adams

Index: Marko, Istvan E.; Mekhalfia, Abdelaziz; Bayston, Daniel J.; Adams, Harry Journal of Organic Chemistry, 1992 , vol. 57, # 8 p. 2211 - 2213

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Citation Number: 62

Abstract

Summary: The Intramolecular Silyl Modified Sakurai (ISMS) reaction is a powerful tool for the construction of tetrahydropyrans, spiroethers, and spiroketals. The ISMS methodology was applied to a short and stereocontrolled synthesis of a minor component of the rectal gland secretion of the female Daws oleae fruit fly.