European journal of medicinal chemistry

Synthesis of novel tetrahydroimidazole derivatives and studies for their biological properties

V Sharma, MSY Khan

Index: Sharma, Vibha; Khan European Journal of Medicinal Chemistry, 2001 , vol. 36, # 7-8 p. 651 - 658

Full Text: HTML

Citation Number: 51

Abstract

Ethylenediamine was reacted with suitable aromatic aldehydes in order to prepare their respective diSchiff bases. These compounds were then reduced to give the corresponding tetrahydrodiSchiff bases, which were low melting in nature. Finally, these derivatives were condensed with different aromatic aldehydes to give the desired tetrahydroimidazoles. The structures of all these compounds were established on the basis of spectral data. These ...