Chromium-mediated asymmetric synthesis of both enantiomers of acetoxytubipofuran

EP Kündig, R Cannas, M Laxmisha…

Index: Feugeas,C.; Olschwang,D. Bulletin de la Societe Chimique de France, 1968 , p. 4985 - 4990

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Citation Number: 44

Abstract

... 9 Selective protection of the primary alcohol as p-methoxybenzyl ether and conversion of the secondary alcohol into the carbonate 12 set the stage ... 4 , CeCl 3 , MeOH, 98%; (b) NaH, PMBI, DMF, 88%; (c) ClCO 2 Me, py, CH 2 Cl 2 , 95%; (d) 6 M NaOH, DMSO, 130 °C, 93%; (e ...