Sulfur as a new low-cost and selective reducing agent for the transformation of benzofuroxans into benzofurazans

…, YV Karpychev, PG Belyaev, GK Khisamutdinov…

Index: Kondyukov; Karpychev; Belyaev; Khisamutdinov; Valeshnii; Smirnov; Il'in Russian Journal of Organic Chemistry, 2007 , vol. 43, # 4 p. 635 - 636

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Citation Number: 3

Abstract

Benzofurazan derivatives exhibit a broad spectrum of biological activity, including antibacterial, antifungal, acaricide, antileukemic, and immunodepressive action [1–3]. An efficient and widely used procedure for the synthesis of these compounds is based on reductive deoxygenation of relatively readily accessible benzofuroxans. Trialkyl-and triarylphosphines, trialkyl phosphites, hydrazine, hydroxylamine, and sodium azide were ...