Tetrahedron

Enzymatic desymmetrization of prochiral 2-benzyl-1, 3-propanediol derivatives: A practical chemoenzymatic synthesis of novel phosphorylated tyrosine analogues

T Yokomatsu, T Minowa, T Murano, S Shibuya

Index: Yokomatsu, Tsutomu; Minowa, Takayuki; Murano, Tetsuo; Shibuya, Shiroshi Tetrahedron, 1998 , vol. 54, # 32 p. 9341 - 9356

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Citation Number: 33

Abstract

(Phosphonomethyl) phenylalanine (Pmp) and (phosphonodifluoromethyl) phenylalanine (F2Pmp) as well as their β-amino acid congeners were prepared as a protecting variant amenable to the peptide synthesis from readily available 2-benzyl-1, 3-propandiols possessing either a diethylphosphonomethyl-or diethylphosphonodifluoromethyl functionality at the para-position via the lipase-catalyzed desymmetrization.

Synthesis of L-2, 3, 5, 6-tetrafluoro-4-(phosphonomethyl) ph...

[Liu, Wang-Qing; Roques, Bernard P.; Garbay, Christiane Tetrahedron Letters, 1997 , vol. 38, # 8 p. 1389 - 1392]

Two crystal structures of human neutrophil collagenase, one ...

[Solas, Dennis; Hale, Ron L.; Patel, Dinesh V. Journal of Organic Chemistry, 1996 , vol. 61, # 4 p. 1537 - 1539]

Synthesis of L-2, 3, 5, 6-tetrafluoro-4-(phosphonomethyl) ph...

[Liu, Wang-Qing; Roques, Bernard P.; Garbay, Christiane Tetrahedron Letters, 1997 , vol. 38, # 8 p. 1389 - 1392]