e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Design, synthesis, and structure-activity relationship of novel dinucleotide analogs as agents against herpes and human immunodeficiency viruses

GH Hakimelahi, AA Moosavi-Movahedi…

Index: Hakimelahi; Moosavi-Movahedi; Sadeghi; Tsay; Jih Ru Hwu Journal of Medicinal Chemistry, 1995 , vol. 38, # 23 p. 4648 - 4659

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Citation Number: 37

Abstract

Gholam H. Hakimelahi,*!',t Ali A. Moosavi-Movahedi,§ Majid M. Sadeghi,t Shwu-Chen Tsay,+ and Jih Ru Hwu*stJ Organosilicon and Synthesis Laboratory, Institute of Chemistry, Academia Sinica, Nankang, Taipei, Taiwan 11529, Republic of China, Faculty of Pharmacy, Zsfahan University of Medical Sciences, Isfahan, Iran, Institute of Biochemistry-Biophysics, Tehran University, Tehran, Iran, and Department of Chemistry, National Tsing Hua University, Hsinchu, ...

1-[3',5'-dideoxy-3'-azido-5'-(dimethylphosphono)-β-D-erythro-pentofuranosyl]thymine Structure

1-[3',5'-dideox...

~77%

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methylphosphonic acid Structure

[(2S,3S,5R)-3-a...

1,4-dihydro-2-methoxy-1-[2',5'-dideoxy-5'-(dimethylphosphono)-3'-O-mesyl-β-D-erythro-pentofuranosyl]-4-oxo-5-methylpyrimidine Structure

1,4-dihydro-2-m...

~74%

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methylphosphonic acid Structure

[(2S,3S,5R)-3-a...

3',5'-Anhydrothymidine Structure

3',5'-Anhydroth...

~%

[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methylphosphonic acid Structure

[(2S,3S,5R)-3-a...

Synthesis of 5′-triphosphate mimics (P3Ms) of 3′-azido-3′, 5...

[Rajwanshi, Vivek K.; Prhavc, Marija; Fagan, Patrick; Brooks, Jennifer L.; Hurd, Tiffany; Cook, P. Dan; Wang, Guangyi Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 3 p. 179 - 189]

Synthesis of 5′-triphosphate mimics (P3Ms) of 3′-azido-3′, 5...

[Rajwanshi, Vivek K.; Prhavc, Marija; Fagan, Patrick; Brooks, Jennifer L.; Hurd, Tiffany; Cook, P. Dan; Wang, Guangyi Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 3 p. 179 - 189]

Synthesis of 5′-triphosphate mimics (P3Ms) of 3′-azido-3′, 5...

[Rajwanshi, Vivek K.; Prhavc, Marija; Fagan, Patrick; Brooks, Jennifer L.; Hurd, Tiffany; Cook, P. Dan; Wang, Guangyi Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 3 p. 179 - 189]

Synthesis of 5′-triphosphate mimics (P3Ms) of 3′-azido-3′, 5...

[Rajwanshi, Vivek K.; Prhavc, Marija; Fagan, Patrick; Brooks, Jennifer L.; Hurd, Tiffany; Cook, P. Dan; Wang, Guangyi Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 3 p. 179 - 189]

Synthesis of 5′-triphosphate mimics (P3Ms) of 3′-azido-3′, 5...

[Rajwanshi, Vivek K.; Prhavc, Marija; Fagan, Patrick; Brooks, Jennifer L.; Hurd, Tiffany; Cook, P. Dan; Wang, Guangyi Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 3 p. 179 - 189]