Molecules

Synthesis and Biological Evaluation of 2, 5-Bis (alkylamino)-1, 4-benzoquinones

…, LV Costa-Lotufo, M Odorico Moraes, C Pessoa

Index: Barbosa, Luiz Claudio Almeida; Pereira, Ulisses Alves; Maltha, Celia Regina Alvares; Teixeira, Robson Ricardo; Valente, Vania Maria Moreira; Ferreira, Jose Roberto Oliveira; Costa-Lotufo, Leticia Veras; Moraes, Manoel Odorico; Pessoa, Claudia Molecules, 2010 , vol. 15, # 8 p. 5629 - 5643

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Citation Number: 18

Abstract

Abstract A series of twelve 2, 5-bis (alkylamino)-1, 4-benzoquinones were prepared in yields ranging from 9–58% via the reaction between p-benzoquinone and various amines. The structures of the synthesized compounds were confirmed by IR, 1 H-and 13 C-NMR and MS analyses. The phytotoxicity of the 2, 5-bis (alkylamino)-1, 4-benzoquinones was evaluated against two crop species, Cucumis sativus and Sorgum bicolor, at 1.0× 10-3 mol/L. In ...