Syntheses and properties of a series of cationic water-soluble phthalocyanines

H Li, TJ Jensen, FR Fronczek…

Index: Li, Hairong; Jensen, Timothy J.; Fronczek, Frank R.; Vicente, M. Graca H. Journal of Medicinal Chemistry, 2008 , vol. 51, # 3 p. 502 - 511

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Citation Number: 119

Abstract

A series of symmetrical cationic phthalocyanines (Pcs) with either Zn (II) or Si (IV) metal ions and two bulky axial ligands on the silicon complexes was synthesized in high yields. The photophysical (absorption, emission, fluorescence, and singlet oxygen quantum yields) and cellular (uptake, toxicity, and subcellular localization) properties of this series of Pcs were investigated. The Si (IV)− Pcs exist mainly as monomers in aqueous media and have ...