A catalyst system comprising 10 mol%(Pd (OAc) and 20 mol% PPh3 effects the cyclisation of aryl halides onto proximate alkenes via 5-, 6-, and 7-exo-trig, and 7-endo-trig processes giving a variety of bridged-ring carbo-and hetero-cycles in excellent yield. Double bond isomerisation in the product is rarley encountered and may be suppressed by the addition of Tl (1) salts. One example of diastereospecific bis-cyclisation is given and the crystal ...
