e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
… Semihollow??Shaped Triethynylphosphane Ligand for Efficient Formation of Six??and Seven??Membered Ring Ethers through Gold (I)??Catalyzed Cyclization of Hydroxy …
Abstract The formation of six-and seven-membered ring ethers from hydroxy-tethered propargylic esters was efficiently catalyzed by a cationic gold (I) complex with a semihollow- shaped triethynylphosphane ligand. This gold catalysis showed a tolerance toward the reactions of primary, secondary, and tertiary alcohol substrates with various substitution patterns. A sterically congested 2, 2, 6, 6-tetraalkyl-substituted tetrahydropyran derivative ...