e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
The Journal of Organic Chemistry
Efficient oxidation of phenyl groups to carboxylic acids with ruthenium tetraoxide. A simple synthesis of (R)-. gamma.-caprolactone, the pheromone of Trogoderma …
MT Nuñez, VS Martin
Index: Nunez, M. Teresa; Martin, Victor S. Journal of Organic Chemistry, 1990 , vol. 55, # 6 p. 1928 - 1932
The oxidation of aromatic rings to carboxylic acids with ruthenium tetraoxide is shown to be a very efficient and simple reaction using periodic acid as the stoichiometric oxidant in a biphasic solvent system (CCl,, CH, CN, H20). The reaction can be very sensitive to the nature of the ring substituents when more than one aromatic ring is present. The procedure is compatible with other functional groups except for those that are quite acid sensitive. A ...