e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Organic letters
… Rh (III)-catalyzed oxidative acylation of secondary benzamides with aldehydes and intramolecular cyclization: The direct synthesis of 3-hydroxyisoindolin-1-ones
S Sharma, E Park, J Park, IS Kim
Index: Sharma, Satyasheel; Park, Eonjeong; Park, Jihye; Kim, In Su Organic Letters, 2012 , vol. 14, # 3 p. 906 - 909
The rhodium-catalyzed oxidative acylation between secondary benzamides and aryl aldehydes via sp2 C–H bond activation followed by an intramolecular cyclization is described. This method results in the direct and efficient synthesis of 3-hydroxyisoindolin-1- one building blocks.
