A biogenetically-inspired synthesis of a ring-D model of kinamycin F: insights into the conformation of ring D

…, MB Carrière, RS Laufer, NJ Taylor, GI Dmitrienko

Index: Liu, Wei; Buck, Matthew; Chen, Nan; Shang, Muhong; Taylor, Nicholas J.; Asoud, Jalil; Wu, Xing; Hasinoff, Brian B.; Dmitrienko, Gary I. Organic Letters, 2007 , vol. 9, # 15 p. 2915 - 2918

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Citation Number: 23

Abstract

An efficient three-step construction of the highly oxygenated D-ring of the kinamycin antibiotics is reported for a simple model system. A comparison of the spectroscopic characteristics of the synthetic models with those of natural kinamycin F, which is suspected