Reactions of aromatic amines with 5-nitro-3-furoyl and 5-nitro-2-furoyl isothiocyanates

A Jurášek, J Štetinová, J Kováč, V Žvak…

Index: Jurasek, Adolf; Stetinova, Jarmila; Kovac, Jaroslav; Zvak, Vladimir; Lesko, Jan; et al Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 3 p. 699 - 705

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Abstract

Abstract 5-Nitro-3-furoyl isothiocyanate reacts with 4-X-anilines (X= H, CH 3, OH, N (C 2 H 5) 2, NHCOCH 3, Cl, Br) to give the corresponding N-(5-nitro-3-furoyl)-N'-(4-X-phenyl) thioureas, in contrast to 4-methoxyaniline and 4-nitroaniline, which afford 5-nitro-3- furancarboxylic acid amides in a rather anomalous way. Formation of these amides is discussed and some properties of 2-and 3-substituted thioureas related to 5-nitrofuran are ...