Journal of the American Chemical Society

Metalation and alkylation of 4H-1, 3-dioxin: A new. beta.-acyl vinyl anion equivalent

RL Funk, GL Bolton

Index: Funk, Raymond L.; Bolton, Gary L. Journal of the American Chemical Society, 1988 , vol. 110, # 4 p. 1290 - 1292

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Citation Number: 41

Abstract

0002-7863/88/15 10-1290 $01.50/0 the a@-unsaturated aldehyde 6 from the alkylated synthetic equivalent. For example, the Corey method requires a hydrolytic step with use of mercuric chloride in warm, aqueous a~ etonitrile.~ In some situations, it may become necessary to generate the a,@-unsaturated aldehyde by using even milder conditions. We describe herein a possible solution to this problem. In particular, we show that a new 0- ...