e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Electronic structure and reactivity of organofluorine compounds
…, NM Karimova, YL Ignatova, AG Matveeva
Index: Rozhkov, I.N.; Karimova, N. M.; Ignatova, Yu. L.; Matveeva, A. G. Russian Chemical Bulletin, 1994 , vol. 43, # 2 p. 258 - 260 Izvestiya Akademi Nauk, Seriya Khimicheskaya, 1994 , # 2 p. 279 - 281
Abstract The basicity of isomeric bromoethylamines having a CF 3 substituent in the α-and β- positions with respect to the amino group was studied. According to potentiometric titration in H 2 O, CH 3 NO 2, and CH 3 CN, the basicity of α-trifluoromethylamines is 4–5 orders of magnitude lower than that of β-trifluoromethyl isomers. Quantum-chemical calculations (AM1) showed that the decrease in the basicity of α-trifluoromethylamines does not ...