Tetrahedron letters

Intraannular functionalization of macrocyclic polyethers via organolithium chemistry; x-ray structure of 2-sulfinyl-1, 3-xylyl-15-crown-4

M Skowronska-Ptasinska, P Telleman, VMLJ Aarts…

Index: Skowronska-Ptasinska, Maria; Telleman, Pieter; Aarts, Veronika M. L. J.; Grootenhuis, Peter D. J.; Eerden, Johan van; et. al. Tetrahedron Letters, 1987 , vol. 28, # 17 p. 1937 - 1940

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Citation Number: 10

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The conversion of 2-lithio-1,3-xylyl crown ethers (2), obtained by reaction of the 2-bromo-1,3- xylyl crown ethers (1) with -butyllithium at −70 °C, with an electrophile is a generally applicable method for the synthesis of 1,3-xylyl crown ethers with intraannular acidic groups.