Il Farmaco

On the relationship between the substitution pattern of thiobenzanilides and their antimycobacterial activity

J Kuneš, V Balšánek, M Pour, K Waisser, J Kaustová

Index: Kunes, Jiri; Balsanek, Vojtech; Pour, Milan; Waisser, Karel; Kaustova, Jarmila Farmaco, 2002 , vol. 57, # 9 p. 777 - 782

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Citation Number: 12

Abstract

The goal of this work was to shed more light on a preliminary finding about the relationship between the substitution in the thioacyl part of thiobenzanilides and their antituberculous effect. Thus, we prepared a set of 14 derivatives, out of which eight had not yet been reported, and the compounds were evaluated for antimycobacterial activity on a panel of four Mycobacteria species, including Mycobacterium tuberculosis CNCTC My 331/88, ...