e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
The formation pathway of 3, 5-bis (methoxymethyl) perhydro-1, 3, 5-oxadiazin-4-one.
…, M Takahashi, T Ebisuno, M Takimoto
Index: Shiba, Ryuichi; Takahashi, Miyuki; Ebisuno, Toichi; Takimoto, Michiaki Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 6 p. 1930 - 1933
The investigation of the reactions of urea and its methyl derivatives with formaldehyde elucidated the formation pathway of 3, 5-bis (methoxymethyl) perhydro-1, 3, 5-oxadiazin-4- one. 1) The addition of formaldehyde to urea became increasingly difficult according to the increase of the number of added formaldehyde molecules, probably because of the steric hindrance of the hydroxymethyl groups. 2) 3, 5-Bis (methoxymethyl) perhydro-1, 3, 5- ...
