... COMMUN., 1987 191 An Efficient Synthesis of 4-Aryl-l,2,3,4-tetrahydroisoquinolines Nurani S. Narasimhan" and Prakash A. Patil Garware Research Centre, Department of Chemistry, University of Poona, Pune 4 1 1 007, India A general synthesis of N-methyl-l,2,3,4- tetrahydroisoquinolines from 3-aryl phthalides is described. In this communication we describe a general synthesis of isoquinoline alkaloid2 with an aryl substituent at the 4 ...