Journal of medicinal chemistry

Arylhydroxamic acid bioactivation via acyl group transfer. Structural requirements for transacylating and electrophile-generating activity of N-(2-fluorenyl) hydroxamic …

HM Yeh, PE Hanna

Index: Yeh, Heui-mei; Hanna, Patrick E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 7 p. 842 - 846

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Citation Number: 13

Abstract

The synthesis of a series of 12 N-(2-fluorenyl) hydroxamic acids, N-(2-fluorenyl)-N- hydroxyureas, and N-(2-fluoreny1)-N-hydroxycarbamates is reported. The compounds were evaluated for their ability to serve as substrates for a partially purified hamster hepatic