Design, synthesis and biological evaluation of thiazole-and indole-based derivatives for the treatment of type II diabetes

Q Xu, L Huang, J Liu, L Ma, T Chen, J Chen…

Index: European Journal of Medicinal Chemistry, , vol. 52, p. 70 - 81

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Citation Number: 18

Abstract

... European Journal of Medicinal Chemistry. ... The coupling constants (J) of these compounds were all between 15.6 and 16.4 Hz in the range from 6.25 to 6.48 ppm in dimethylsulfoxide (DMSO)-d 6 solution, while the values of the Z-isomer were commonly between 7 and 12 ppm ...

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Direct preparation of thiazoles, imidazoles, imidazopyridine...

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