Prodrug strategy for PSMA-targeted delivery of TGX-221 to prostate cancer cells

Y Zhao, S Duan, X Zeng, C Liu, NM Davies…

Index: Molecular Pharmaceutics, , vol. 9, # 6 p. 1705 - 1716

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Citation Number: 28

Abstract

... a novel formulation approach for improving site-specific drug delivery of a molecular-targeted prostate ... The synthetic small molecule TGX-221 (Figure 1) is a potent, selective, and cell membrane ... have been used as an effective drug delivery system for lipophilic molecules.(21-23 ...