e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

(-)-4-Hydroxymorphinanones: their synthesis and analgesic activity

A Manmade, HC Dalzell, JF Howes…

Index: Manmade; Dalzell; Howes; Razdan Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1437 - 1440

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Citation Number: 13

Abstract

The antinociceptive activity of these compounds is shown in Table I. It was determined both in the acetic acid induced mouse writhings and the heat stimulus rat tail-flickg tests. The narcotic antagonist activity was determined by the rat tail-flick methode against an EDw of morphine.

(-)-4,5-epoxymorphinan-6-one Structure

(-)-4,5-epoxymo...

~%

Ketorfanol Structure

Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid...

[Ida, Yoshihiro; Nemoto, Toru; Hirayama, Shigeto; Fujii, Hideaki; Osa, Yumiko; Imai, Masayuki; Nakamura, Takashi; Kanemasa, Toshiyuki; Kato, Akira; Nagase, Hiroshi Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 949 - 961]

Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid...

[Ida, Yoshihiro; Nemoto, Toru; Hirayama, Shigeto; Fujii, Hideaki; Osa, Yumiko; Imai, Masayuki; Nakamura, Takashi; Kanemasa, Toshiyuki; Kato, Akira; Nagase, Hiroshi Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 949 - 961]

Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid...

[Ida, Yoshihiro; Nemoto, Toru; Hirayama, Shigeto; Fujii, Hideaki; Osa, Yumiko; Imai, Masayuki; Nakamura, Takashi; Kanemasa, Toshiyuki; Kato, Akira; Nagase, Hiroshi Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 949 - 961]

Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid...

[Ida, Yoshihiro; Nemoto, Toru; Hirayama, Shigeto; Fujii, Hideaki; Osa, Yumiko; Imai, Masayuki; Nakamura, Takashi; Kanemasa, Toshiyuki; Kato, Akira; Nagase, Hiroshi Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 949 - 961]