4, 5??Dihydroisoxazole and 4, 5??dihydro??1, 2, 4??oxadiazole derivatives from cycloaddition reactions of nitrile oxides to alkyl N??(diphenylmethylene)?螃?, β?? …

…, G Tarzia, M Lanfranchi, MA Pellinghelli

Index: Balsamini, Cesarino; Spadoni, Gilberto; Bedini, Annalida; Tarzia, Giorgio; Lanfranchi, Maurizio; Pellinghelli, Maria Angela Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 6 p. 1593 - 1598

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Citation Number: 14

Abstract

Abstract The alkyl N-(diphenylmethylene)-α, β-dehydroamino acids 1 have been submitted to 1, 3-dipolar cycloadditions with nitrile oxides. The reactivity of these compounds depends on the type and on the stereochemistry of the β-substituents. With the unsubstituted terms 1a, b the reaction occurs on the C, C double bond, providing a good method for the synthesis of the 4, 5-dihydroisoxazole derivatives 3a, b, c and for the gem-functionalized 4 ...