Synthesis and structure–activity relationships of phenothiazine carboxylic acids having pyrimidine-dione as novel histamine H 1 antagonists

K Kubota, H Kurebayashi, H Miyachi, M Tobe…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 10 p. 2766 - 2771

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Citation Number: 29

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... On the other hand, ITR was primarily caused by IgE-mediated activation of mast cells/basophils to release chemical mediators such as histamine, 4 and 7 and anti-histamines (Fexofenadine and Ketotifen fumarate, vide post, Table 1 ...