Investigations in the vitamin B6??series: I. synthesis of nor??vitamin B6

B Van der Wal, TJ de Boer…

Index: van der Wal,B. et al. Recueil des Travaux Chimiques des Pays-Bas, 1961 , vol. 80, p. 203 - 216

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Citation Number: 3

Abstract

Abstract The synthesis is described of nor-vitamin B 6 (nor-pyridoxol) by a selective demethylation of a suitable vitamin B 6 precursor. The demethylation is accomplished in a three step process following the sequence CH 3 [RIGHTWARDS ARROW] CHO [RIGHTWARDS ARROW] COOH [RIGHTWARDS ARROW] H, in which SeO 2 appears to be a particularly selective oxidant for the first step. The nor-vitamin B 6 proves to be ...