Tetrahedron Letters

A new strategy for the stereoselective synthesis of 2, 2′-bipyrrolidines

MJ Gresser, PA Keller, SM Wales

Index: Gresser, Mary J.; Keller, Paul A.; Wales, Steven M. Tetrahedron Letters, 2009 , vol. 50, # 34 p. 4899 - 4902

Full Text: HTML

Citation Number: 8

Abstract

A new strategy for the stereoselective synthesis of the 2, 2′-bipyrrolidine scaffold is presented using a metathesis reaction followed by asymmetric dihydroxylation for the introduction of the stereogenic elements. This straightforward high-yielding process is suitable for application to the synthesis of additional heterocycles.