Synthesis and antifungal evaluation of pentyloxyl-diphenylisoxazoloyl pneumocandins and echinocandins

SB Singh, K Herath, JN Kahn, P Mann…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 11 p. 3253 - 3256

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Citation Number: 4

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Departments of Medicinal Chemistry and Infectious Disease ... Chemistry: Coupling of the mono-methyl ester of benzene-1,4-dicarboxylic acid (3) with t-butyl-hydroxyl amine with DEPC produced the hydroxy amide (4) in 95% yield. ...