Synthesis

Dess-Martin periodinane mediated intramolecular cyclization of phenolic azomethines: a solution-phase strategy toward benzoxazoles and benzothiazoles

DS Bose, M Idrees

Index: Bose, D. Subhas; Idrees, Mohd. Synthesis, 2010 , # 3 p. 398 - 402

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Citation Number: 18

Abstract

Abstract Dess-Martin periodinane (DMP), a highly versatile hypervalent iodine (V) reagent, was found to efficiently mediate the intramolecular cyclization of phenolic azomethines/Schiff bases at ambient temperature leading to the rapid and expeditious synthesis of substituted benzoxazoles and benzothiazoles. Furthermore, a solution-phase strategy has been developed by treating the reaction mixtures sequentially with Amberlyst A-26 thiosulfate ...