Organic & biomolecular chemistry

Solvent-free mechanochemical and one-pot reductive benzylizations of malononitrile and 4-methylaniline using Hantzsch 1, 4-dihydropyridine as the reductant

Z Zhang, J Gao, JJ Xia, GW Wang

Index: Zhang, Ze; Gao, Jie; Xia, Jing-Jing; Wang, Guan-Wu Organic and Biomolecular Chemistry, 2005 , vol. 3, # 9 p. 1617 - 1619

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Citation Number: 67

Abstract

Chemical hydrogenations of double bond-containing compounds including imines, benzylidenemalononitriles and various other α,β-unsaturated systems often involve the use of metal catalysts 1 or stoichiometric amount of metal hydrides. 2 In these cases there are some drawbacks, such as the use of expensive and even toxic metals, relatively low chemoselectivity and so on. To circumvent these problems one of the best alternatives is to apply organoreductants, which have been arousing great ...