Abstract Alkylation of 5-aryl (hetaryl) tetrazoles with methyl chloromethyl ether under conditions of phase-transfer catalysis leads to formation of isomeric 1-and 2- methoxymethyltetrazoles at a ratio of~ 1: 2. The reaction of 5-substituted tetrazoles with α- methylstyrene in the presence of trichloroacetic acid gives the corresponding 2-(α, α- dimethylbenzyl) tetrazoles in high yield and with high regioselectivity.
