Synthesis, biological evaluation, X-ray structure, and pharmacokinetics of aminopyrimidine c-jun-N-terminal kinase (JNK) inhibitors

T Kamenecka, R Jiang, X Song, D Duckett…

Index: Journal of Medicinal Chemistry, , vol. 53, # 1 p. 419 - 431

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Citation Number: 40

Abstract

... Journal of Medicinal Chemistry. ... From a chemistry perspective, numerous JNK selective inhibitors have begun to emerge and include compounds from classes such as indazoles,(10, 11) aminopyrazoles,(11) aminopyridines,(12, 13) pyridine carboxamides,(13, 14) benzothien ...