Tetrahydro thiadiazolo isoquinolines: synthesis and inhibition of phenylethanolamine-N-methyltransferase

GR Girard, WE Bondinell, LM Hillegass…

Index: Journal of Medicinal Chemistry, , vol. 32, # 7 p. 1566 - 1571

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Citation Number: 14

Abstract

... of 5 while the piperidino ring is puckered into a twist-chair form with N1 and the adjacent c6 atoms on opposite sides of the c7-c8-c4-c5 plane (see Figure 1; the atom numbering is not according to Chemical Abstracts numbering ... 1570 Journal of Medicinal Chemistry, 1989, Vol ...