4-Anilino-6, 7-dialkoxyquinoline-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6, 7- …

A Wissner, DM Berger, DH Boschelli…

Index: Journal of Medicinal Chemistry, , vol. 43, # 17 p. 3244 - 3256

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Citation Number: 178

Abstract

... Journal of Medicinal Chemistry. ... 17 Several pharmaceutical firms, 18 including ourselves, 19 established programs based on these inhibitors, and now at least three such compounds have entered or will be entering clinical trials. ...