Tetrahedron letters

A mild and general method for the synthesis of 2-substituted-5-hydroxypyrimidines

JR Medina, TA Henry, JM Axten

Index: Medina, Jesus R.; Henry, Theresa A.; Axten, Jeffrey M. Tetrahedron Letters, 2006 , vol. 47, # 41 p. 7363 - 7365

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Citation Number: 4

Abstract

5-Bromopyrimidines are converted to 5-hydroxypyrimidines using a mild synthetic procedure. The method is general and can be applied to compounds containing functional groups which are not compatible with the other reagents previously available for this conversion.