In Situ–Generated Zinc Bromide–Catalyzed α??Bromination of Alkanones in Water

SK Juneja, D Choudhary, S Paul…

Index: Juneja, Satinder K.; Choudhary, Deepak; Paul, Satya; Gupta, Rajive Synthetic Communications, 2006 , vol. 36, # 19 p. 2877 - 2881

Full Text: HTML

Citation Number: 7

Abstract

Abstract α??Bromination of alkanones with bromine catalyzed by in situ–generated zinc bromide from zinc dust and bromine in water is investigated. Bromination with dioxane?? dibromide as a source of bromine does not require zinc dust and provides selectively α?? mono and α, α??dibromo products in excellent yields when water is used as solvent.

~94%

~74%

~85%

Silica gel catalyzed α-bromination of ketones using N-bromos...

[Mohan Reddy, Bodireddy; Venkata Ramana Kumar, Velpula; Chinna Gangi Reddy, Nallagondu; Mahender Rao, Siripragada Chinese Chemical Letters, 2014 , vol. 25, # 1 p. 179 - 182]

Silver Acetate Mediated Acetoxylations of Alkyl Halides

[Nolla-Saltiel, Roberto; Carrillo-Arcos, Ulises Alonso; Porcel, Susana Synthesis (Germany), 2014 , vol. 46, # 2 p. 165 - 169]

Tandem oxidation/bromination of ethyl aromatics to α, α-dibr...

[Tada, Norihiro; Ban, Kazunori; Ishigami, Takafumi; Nobuta, Tomoya; Miura, Tsuyoshi; Itoh, Akichika Tetrahedron Letters, 2011 , vol. 52, # 29 p. 3821 - 3824]

Synthesis of dibromo ketones by the reaction of the environm...

[Terentev, Alexander O.; Krylov, Igor B.; Vil, Vera A.; Pastukhova, Zhanna Yu.; Fastov, Sergey A.; Nikishin, Gennady I. Central European Journal of Chemistry, 2012 , vol. 10, # 2 p. 360 - 367]