Inhibition of reductive elimination of diorganopalladium species by formation of tetraorganopalladates

E Negishi, K Akiyoshi, T Takahashi

Index: Negishi, Ei-ichi; Akiyoshi, Kazunari; Takahashi, Tamotsu Journal of the Chemical Society, Chemical Communications, 1987 , # 6 p. 477 - 478

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Citation Number: 29

Abstract

Reductive elimination of (tBuCC) 2Pd (PPh3) 2 to give tBuCCCCBut (4) is strongly inhibited by an excess of LiCCBut through the formation of Li2Pd (CCBut) 4, which does not readily decompose to produce (4); these results provide, for the first time, a mechanistic interpretation of the hitherto puzzling inhibitory action of highly electropositive metals, such as Li, in Pd-promoted coupling reactions.