The optimization of aminooxadiazoles as orally active inhibitors of Cdc7

PE Harrington, MP Bourbeau, C Fotsch, M Frohn…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 23 p. 6396 - 6400

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Citation Number: 5

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... a Medicinal Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA; ... The chemical matter leading to 1 was identified through high throughput screening of analogs from our protein kinase B (PKB) program. ...

7-Azaindole derivatives as potential partial nicotinic agoni...

[Stoit, Axel R.; den Hartog, Arnold P.; Mons, Harry; van Schaik, Sjoerd; Barkhuijsen, Nynke; Stroomer, Cees; Coolen, Hein K.A.C.; Reinders, Jan Hendrik; Adolfs, Tiny J.P.; van der Neut, Martina; Keizer, Hiskias; Kruse, Chris G. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 188 - 193]