3-Aminopiperidin-2-one and α-amino-ε-caprolactam were efficiently resolved by inclusion complexation with a chiral host compound,(R, R)-(−)-trans-4, 5-bis (hydroxydiphenylmethyl)- 1, 4-dioxaspiro [4.5] decane. The amino substituent on the lactam ring was found to play an important role in efficient chiral recognition in the inclusion crystals.
