e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Carbohydrate Research
Synthesis of 2-acetamido-2-deoxy-3-O-β-d-galactopyranosyl-d-galactopyranose from 2-acetamido-2-deoxy-d-glucose through a trifluoromethylsulfonyl group …
The carbohydrate sequence BD-Galp-(1+ 3)-D-GalNAc is widely distributed in nature, either in 0-glycoproteins or in glycolipids such as the gang&gangliosides. In 0-glycoproteins, this disaccharide is linked a-~-(1+ 3) to serine or threonine, and usually further glycosylated. On the contrary, alteration in glycosylation, often associated with malignancy, results in its appearance in glycoconjugates. Such structure, the socalled T-antigen, which is present ...