Zinc-mediated carbon radical addition to glyoxylic imines in aqueous media for the synthesis of α-amino acids

M Ueda, H Miyabe, H Sugino, T Naito

Index: Organic and Biomolecular Chemistry, , vol. 3, # 6 p. 1124 - 1128

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Citation Number: 28

Abstract

... proceeded to give the good yields of the products 6b–e (Table 3, entries 3–6). These chemical yields were ... 2 : 1, v/v) did not proceed effectively (Table 4, entry 2). In the absence of organic cosolvent, the ... ii) H 2 , Pd(OH) 2 /C, CSA, MeOH, 20 °C; iii) CbzCl, Na 2 CO 3 , acetone–H ...