Synthesis of Homochiral Acyclic Mono-and Bis (α-amino acid) s with Oligo (oxyethylene) Chains

M Bělohradský, L Ridvan, J Závada

Index: Belohradsky, Martin; Ridvan, Ludek; Zavada, Jiri Collection of Czechoslovak Chemical Communications, 2003 , vol. 68, # 7 p. 1319 - 1325

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Citation Number: 2

Abstract

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague, Czech Republic; e-mail: 1 martinb@uochb.cas.cz, 2 zavada@uochb.cas.cz ... Synthesis of homochiral α-amino acids 3a–3e and bis(α-amino acid)s 4a–4e via BF3·Et2O- catalyzed ring-opening of methyl (S)-1-[(benzyloxy)carbonyl]aziridine -2-carboxylate (7) with oligo(ethylene glycol)s and subsequent acid hydrolysis is ...